CASPIAN JOURNAL
MANAGEMENT AND HIGH TECHNOLOGIES
DISTRIBUTED AUTONOMOUS INTELLECTUAL AGENTS FOR MONITORING AND META-ANALYSIS OF LIVING SYSTEMS MANAGEMENT EFFECTIVENESS
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Read | Petrova Tatyana V., Kuzmin Aleksandr A., Savinov Denis Yu, Strebrovskiy Vadim V. DISTRIBUTED AUTONOMOUS INTELLECTUAL AGENTS FOR MONITORING AND META-ANALYSIS OF LIVING SYSTEMS MANAGEMENT EFFECTIVENESS // Caspian journal : management and high technologies. — 2017. — №4. — pp. 61-73. |
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Petrova Tatyana V. - applicant, South-West State University, 94, 50 let Oktyabrya St., Kursk, 305040, Russian Federation, ptata@ya.ru
Kuzmin Aleksandr A. - Cand. Sci. (Engineering), Associate Р rofessor, South-West State University, 94, 50 let Oktyabrya St., Kursk, 305040, Russian Federation, ku3bmin@gmail.com
Savinov Denis Yu - post-graduate student, South-West State University, 94, 50 let Oktyabrya St., Kursk, 305040, Russian Federation, Filist@gmail.com
Strebrovskiy Vadim V. - Doct. Sci. (Engineering), Professor, South-West State University, 94, 50 let Oktyabrya St., Kursk, 305040, Russian Federation, kstu-bmi@yandex.ru
The article considers the issues of constructing decision support systems for forecasting and monitoring the effectiveness of living systems control, in particular, ensuring the effectiveness of therapeutic procedures (ETP). ETP control is implemented in three stages. At the first stage, surrogate markers are selected and the decision on ETP is made through their monitoring. At the second stage, a distributed database is created which allows to create the surrogate markers intended for ETP monitoring. The third stage gives a meta-analysis of the information collected in the distributed database on surrogate markers and its results influence the decision on the ETP. The tool for creating a distributed database is the interior, which is a software module for conducting research using Internet technologies. With the help of its software, the experimenter can create a community of remote users who can provide him with the information about the characteristics of surrogate markers measured during the control actions on the living system. Based on this information, the dynamics of the functional state of a person (a living system) is estimated. Thus, the chain is realized: pathology - therapeutic procedure - surrogate marker - meta-analysis. Though, the interior doesn’t realize the procedure for selecting a surrogate marker. Tools for the implementation of the interior represent a web service. The interior software is designed to work with a web service, which is the manager of both the distributed database and the community of interiors. A web service presents an example in which surrogate markers are selected based on analysis of intercellular relationships of peripheral blood smears. The article gives algorithmic support of the web service and the structure of its software modules, and it also describes the functional interaction of the developed software modules and the structure of the module for monitoring the dynamics of intercellular relations providing a meta-analysis of the effectiveness of drug prescriptions. The author gives a description of the developed appropriate procedures for the analysis and classification of images of peripheral blood smears to ensure the functioning of the module for the analysis of the dynamics of intercellular relationships in the process of medicinal prescriptions. The obtained results will be in demand among both medical institutions and educational institutions, as well as the organizations of various forms of ownership working in the field of health and pharmacology.
Key words: мониторинг эффективности терапевтических процедур, системы поддержки принятия решений, интернет-технологии, интерьер, суррогатный маркер, веб-сервис, алгоритм, программное обеспечение, therapeutic procedures effectiveness monitoring, decision support syst