CASPIAN JOURNAL
MANAGEMENT AND HIGH TECHNOLOGIES
Model for estimation of erythrocytes aggregation level by optoacoustic method
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Read | Kravchuk D.A., Starchenko I.B. Model for estimation of erythrocytes aggregation level by optoacoustic method // Caspian journal : management and high technologies. — 2017. — №4. — pp. 174-183. |
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Kravchuk D.A. - Cand. Sci. (Engineering), Associate Professor, Southern Federal University, 2 Shevchenko St., Taganrog, 347922, Russian Federation, Kravchukda@sfedu.ru
Starchenko I.B. - Doct. Sci. (Engineering), Professor, Southern Federal University, 2 Shevchenko St., Taganrog, 347922, Russian Federation, ibstarchenko@gmail.com
The paper dwells on issues of mathematical modeling of aggregation of erythrocytes - one of human blood formed elements. The results of computational experiments allow to conclude that it is possible to register the degree of erythrocytes aggregation with the use of an optoacoustic effect that arises as a result of the action of IR laser radiation on model cells in a liquid medium. The optoacoustic method techniques make it possible to provide better accuracy and contrast in comparison with ultrasonic methods and to increase the depth of penetration in comparison with optical methods. Techniques that can be used during the formation of an optoacoustic signal have different efficiency for different processes: absorption (ablation and dielectric breakdown) and nonabsorption (electrostriction and exposure to optical radiation pressure). Changes in temperature are due to local heating of the liquid at the spot of the laser radiation pulses effect. In this case, the processes of thermal expansion of the volume under radiation occur. This generates the appearance of ultrasonic waves, which can spread both in the liquid itself (blood) and in the soft tissues of the body. The latter, in turn, provides the potential for conducting non-invasive studies in clinical practice.
Key words: лазер, диагностика, оптоакустические волны, биожидкость, сферический поглотитель, гематокрит, спектральная плотность сигнала, эритроциты, агрегация, гематокрит, уровень агрегации, laser, diagnostics, optoacoustic waves, biofluid, spherical absorber, hemat