CASPIAN JOURNAL
MANAGEMENT AND HIGH TECHNOLOGIES
The application of the ouycomes of the statistical analysis of the viral and bacterial markers influence on the clinical picture of the disease in diagnostic decisions
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Read | Dedov Aleksey V., Popov Georgiy A. The application of the ouycomes of the statistical analysis of the viral and bacterial markers influence on the clinical picture of the disease in diagnostic decisions // Caspian journal : management and high technologies. — 2014. — №4. — pp. 119-133. |
Dedov Aleksey V. - Astrakhan State Medical Academy, 121 Bakinskaya St., Astrakhan, 414000 Russian Federation, dedov1965.d@yandex.ru
Popov Georgiy A. - D.Sc. (Engineering), Professor, Astrakhan State Technical University, 16 Tatishchev St., Astrakhan, 414025, Russian Federation, popov@astu.org
The article is devoted to the creation of the procedure for the evaluation of the interrelation degree between the disease and the viral and bacterial markers that could be the basement of diagnostic decisions. This procedure was realised on the basis of mathematical, statistical methods with the special relation to the influence of viral and bacterial markers to the significant characteristics of clinical picture of chronic diffuse liver diseases (CDLD).The researches were based on the large diagnostic information collected during many years (165 patients). To solve this problem, the authors had used the multidimensional modification of the classical Mann - Whitney method for the checking the hypothesis of the uniformity of two choises. On the basement of the offered method the most significant markers were revealed with the 5 % significance level. Then 8 of 26 investigated markers were detected as the relevant ones. For statistically significant markers the analysis of their interrelations with the diagnostic signs was carried out. The results of the analysis were reflected in three tables. In the first one for each significant marker the most important diagnostic signs connected with it were listed. In the second table the interrelations between most important parameters with statistically significant markers were presented. In the third table the full information about the interrelation between markers themselves on the basis of their mutual correlations was given.
Key words: принятие диагностических решений, метод Манна - Уитни, многомерное обобщение, корреляционный анализ, вирусно-бактериальные маркеры, хронические заболевания печени, Прикаспийский регион, diagnostic decisions, Mann - Whitney method, multidimensional modific